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Advise females of reproductive potential to use effective contraception during IBRANCE treatment and for at least 3 weeks after the last dose. HER2- advanced or metastatic breast cancer in combination with endocrine therapy. The dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may impair fertility in myambutol price comparison males and has the potential to cause genotoxicity.

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IBRANCE is 75 mg. Monitor complete blood count prior to starting IBRANCE, at the beginning of each cycle, on Day 15 of first 2 cycles and as clinically indicated. Advise women not to breastfeed during IBRANCE treatment and for 3 weeks after the last dose because of the potential to cause genotoxicity.

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